Short RNAs: How Big Is This Iceberg?

نویسنده

  • Isidore Rigoutsos
چکیده

Recent studies have reported the identification of piwi-associated RNAs (piRNAs) in Drosophila somatic cells. Interestingly, these piRNAs derive from the 3' untranslated regions of a subset of transcribed protein-coding genes and, experimentation suggests, might control the expression of other protein-coding transcripts. Studies of additional organisms support the new pathway's presence across animals.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of Wind Turbine, Solar Cells and Storages in Short Term Operation of Coupled Electricity and Gas Infrastructures in Different Climates

The biggest challenges faced in big cities are greenhouse gas emission and growing energy needs. Efficient utilization of existing infrastructures has a prominent role in response to the challenges. Energy hub approach embraces performance of different energy networks. Energy hub is defined as a super node in electrical system receiving distinctive energy carriers such as gas and electricity in...

متن کامل

The Complementary Iceberg Tips of Diabetes and Precision Medicine

Introduction There appears to be a chronic lack of confidence in global healthcare systems. Stakeholder expectations have been fueled by repetitive media reports of spectacular advances in the diagnosis and treatment of the major diseases that afflict patients. However, those same patients perceive a lack of delivered value from their healthcare provider. In part this is predicated on the trans...

متن کامل

On: Milgrom LR: Under pressure: homeopathy UK and its detractors. Forsch Komplementmed 2009;16:256-261.

Milgrom’s article was certainly the most amusing, uplifting and revealing bit of alternative fiction I have read for a very long time. Amusing because the arguments of the authors are truly funny. I am on the top of the ‘Big Pharma’ iceberg trying to crush homeopathy!?! Why would ‘Big Pharm’ bother? Homeopathy only amounts to 0.006% of the total National Health Service (NHS) budget, as Milgrom ...

متن کامل

I-38: New and Old Technologies in the Modern IVF Clinic

Background PGD has been around in various forms for over a quarter of a century now. During this time it has evolved from simple FISH and direct PCR mutation analysis to whole chromosome profiling using microarrays or next generation sequencing and improved monogene testing using STR linkage or now, recombination mapping. Modern PGD can now deliver highly accurate and reproducible results capab...

متن کامل

Micro-RNAs

Two small temporally regulated RNAs (stRNAs)* of approximately 22 nucleotides regulate timing of gene expression during development of the nematode C. elegans. This regulation occurs at a posttranscriptional, presumably translational, level and is distinct from RNA interference (RNAi). One of the two stRNAs, let-7, as well as its target gene, lin-41, are highly conserved even in humans, suggest...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Current Biology

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2010